Gluformin

Metformin is an oral medication. It is used to treat a type of diabetes mellitus called type 2 diabetes. In this type of diabetes, insulin produced by the pancreas gland is not able to get sugar into the cells of the body where it can work properly. To get maximum advantages from this medication, the amount of metformin you take must be balanced against the amount and type of food you eat and the amount of exercise you do. However, this medication does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections. This medication is available only with your doctor's prescription, in the Oral Tablets form. The FDA approved this medication in December, 1994.

Preparations:

• Metformin tablets: 500, 850, and 1000 mg.
• Glucophage XR (extended release) tablets: 500 and 750 mg.
• Glumetza tablets (extended release) 500 and 1000 mg.

Generic Name

Metformin

Mexican Name

Glucopage

Usage Information

This medication is best taken by mouth with meals. Drink plenty of fluids while taking this medication. In order to get the most benefit from this medication, use it regularly and that at the same time each day.

Dosage

For adults, metformin usually is begun at a dose of 500 mg twice a day or 850 mg once daily. The dose is gradually increased by 500 mg weekly or 850 mg every two weeks as tolerated and based on the response of the levels of glucose in the blood. The maximum daily dose is 2550 mg given in three divided doses. If Glucophage XR tablets are used, the starting dose is 500 mg daily with the evening meal. The dose can be increased by 500 mg weekly up to a maximum dose of 2000 mg once daily or in two divided doses. Glumetza tablets are given once daily.

Interactions

This medication interacts with Cimetidine by decreasing the elimination of metformin from the body. This can increase the amount of metformin in the blood by 40%.

Side Effects

Nausea, stomach upset, diarrhea or metallic taste may occur initially as your body adjusts to the medication. If stomach symptoms recur later, tell your doctor immediately. A late recurrence of stomach symptoms may be due to lactic acidosis.

Warnings Recalls

Some time, this medication can cause a condition called lactic acidosis, which can be fatal. Lactic acidosis is more likely to occur in patients who have: kidney or liver disease, excessive alcohol use, dehydration etc.

Trade Names USA

Glucophage, Glucophage XR, Glumetza

Trade Names Canada

Apo-Metformin, Gen-Metformin, Glucophage, Glycon, Novo-Metformin, Nu-Metformin

Trade Names Mexico

Dabex, Dimefor, Glucophage

Trade Names Other Countries

Gluformin L, Gluformin, Bigesens, Bigomet, Cetapin, Diaformin, Diamet, Dibeta-SR, Dibimet, E met, Emfor, Zetfor, Zomet.

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